Let us walk you through our variety of testing for vesiculo bullous disease.
Vesiculo-Bullous Disease Testing
The detection of anti-skin antibodies aids in the diagnosis and prognosis of chronic vesiculo-bullous diseases, including pemphigus, pemphigoid, mucous membrane (cicatricial) pemphigoid, and epidermolysis bullosa acquisita (EBA). Epithelial intercellular (IC) antibodies are diagnostic for pemphigus. Antibodies to basement membrane zone (BMZ) antigens of stratified squamous epithelium occur in active bullous pemphigoid (BP), vesicular pemphigoid, EBA and mucous membrane (cicatricial) pemphigoid patients. Serological differentiation of
bullous pemphigoid from EBA can be aided by utilizing tests employing in split skin sections.
Dermatitis Herpetiformis (DH) and be identified utilizing tests and profiles for Endomysial (EMA) IgA antibody, Reticulin (ARA) IgA antibody, and Deamidated Gliadin (Celiac G+) antibody IgA and IgG.
For testing of Chronic Ulcerative Stomatitis (CUS), SES-ANA stratified epithelium specific
antinuclear antibodies can be helpful in diagnosis.
Reference Lab Services
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129 Pemphigus/Pemphigoid Profile I includes IC and BMZ antibodies (dual substrate) Differentiation of BP from EBA on “split skin” Desmoglein 1 (DSG1) antibody Desmoglein 3 (DSG3) antibody Bullous Pemphigoid 180 (BP 180) antibody Bullous Pemphigoid 230 (BP 230) antibody
Dermatitis Herpetiformis (DH)
For an overview of Immco’s Immunogenetics testing, tap or click here.
Chronic Ulcerative Stomatitis (CUS)
For an overview of Immco’s testing, tap or click here.