COVID-19
The highly accurate Captia™ SARS CoV-2 antibody testing is available utilizing ELISA. This test has a sensitivity value of 97.9% to 100% and specificity values of 97.7% to 100%.
COVID-19Testing
New COVID-19 Related Autoimmune / Vasculitis Panel
Autoimmune manifestations are commonly encountered in COVID-19 patients. Of particular note is the recently described cross-reactivity between the SARS CoV-2 spike protein and extractable nuclear antigens (ENA). This warrants screening patients for anti-nuclear antibodies (ANA) and confirmatory testing with a comprehensive panel of ENA.
Kawasaki-like vasculitis is also a potential complication of SARS CoV-2 infection, primarily in children but frequently in adults. Contributing factors to COVID related vasculitis include circulating immune complexes and anti-cardiolipin antibody (ACA). Identification of these factors may aid in the prevention of adverse thrombotic events.
Immco’s new COVID-19 Related Autoimmune/Vasculitis Panel will help you diagnose patients with manifestations of autoimmune diseases after contracting COVID-19. This comprehensive panel will be read by an immunologist and will help you in the treatment of your patients.
This panel includes:
| ANA | ||
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dsDNA
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| ANCA | ||
| Anti-cardiolipin antibody (ACA) IgG, IgA, IgMz | ||
| Immune Complexes (CIC) | ||
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SSA/Ro
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Centromere
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U1 Sn RNP A
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SSA/La
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PM/Scl-100
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U1 Sn RNP C
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PM/Scl-75
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Mi-2
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SM
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Jo-1
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Ku
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U1 Sn RNP 68
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SRP 54
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5-10ml of blood in a red top or serum separator tube. Specimen collection kits are available free of charge by clicking the “Request Test Kits” button above, call 800-537-8378, or email laboratoryservices@immco.com.
References
- Rodríguez Y, Novelli L, et al. Autoinflammatory and autoimmune conditions at the crossroad of COVID-19. Journal of Autoimmunity 114 (2020) 102506
- Woodruff M, Ramonell R, Eun-Hyung Lee F, Sanz I (2020). “Broadly-targeted autoreactivity is common in severe SARS C0V-2 Infection” medRxiv 10.21.20216192
- Icenogle T (2020). “COVID-19: Infection or Autoimmunity” Frontiers in Immunology 11: 9-11
- Talotta R, Robertson E (2020). “Autoimmunity as the comet tail of COVID-19 pandemic” World Journal of Clinical Cases 17: 3621-3644
- Yu Z, Estes S, Ali R, et al (2020). ”Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19” Science Translational Medicine Nov 2; eabd3876
- Almashat S A (2020). “Vasculitis in COVID-19: A Literature Review” Journal of Vasculitis 6: 1,2020
COVID-19 Molecular PCR testing
A molecular test is available to test symptomatic patients for COVID-19. The PCR testing that we use for transplant patients is utilized to detect the presence of SARS-CoV-2. PCR testing is considered the most accurate COVID-19 test available.
Immco is committed to serve our Western New York Community by doing our part to help with the COVID-19 pandemic. We are here to serve health care professionals to get the answers you need as quickly as possible.
Specimen collection and processing
If you suspect your patient has COVID-19, please collect a nasopharyngeal swab sample. Specimen collection kits are available free of charge by clicking the “Request Test Kits” button above, call 800-537-8378, or email laboratoryservices@immco.com.
Storage Instructions
Room temperature swabs can be sent if received within 24 hours of collection. Refrigerated specimens can be used if received for testing within 72 hours of collection.
COVID-19 Antibody testing
The Trinity Biotech Captia™ SARS CoV-2 IgG EIA kit is used to detect IgG antibodies to S1 & S2 spike antigens of the SARS CoV-2 Virus in serum and plasma. Manufactured with recombinant antigens, crucial for maximum sensitivity and specificity.
- Excellent Performance 95.1% Sensitivity / 98.2% Specificity
Sample Submission
5-10ml of blood in a red top or serum separator tube. Specimen collection kits are available free of charge by clicking the “Request Test Kits” button above, call 800-537-8378, or email laboratoryservices@immco.com.