|Disease:||• Scleroderma • Antibodies to Extractable Nuclear (ENA) & Cytoplasmic Antigens|
|Reference Range:||Negative: <20 ; Borderline: 20-25 ; Positive: >25|
|Schedule / Turnaround Time:||Assay performed once per week. Report availability is within one week from the time of specimen receipt.|
Specimen need not be refrigerated or frozen. Collect 2-3 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into white tube provided with Immco Diagnostics’ collection kits. If separation facilities are not available, the blood can be sent in the tube used for collection.
Sample is stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8˚C) up to five days and frozen (-20˚C or lower) up to one year.
Antibodies to RNP occur in 35-45% of systemic lupus erythematosus patients and in over 95% of patients with mixed connective tissue disease.