| Test Number | 171 |
| Method | ELISA |
| Reference Range |
Negative <20 Units (U)
Weak Positive (equivocal) 20-30 U
Moderate to strong Positive > 30 U
|
| CPT Code | 86235 |
| Schedule Turnaround Time | Assay performed once every two weeks. Report availability is two weeks from the time of specimen receipt. |
| Specimen Requirements | Specimen need not be refrigerated or frozen. Collect 4-10 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into orange tube provided with IMMCO collection kits. Do not puncture top of orange tube. If separation facilities are not available, the blood can be sent in the tube used for collection.
Requested Sample Volume: 2 mL
Minimum Sample Volume: 0.5mL |
| Sample Stability | Sample is stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8˚C) up to five days and frozen (-20˚C or lower) up to one year.
Cause for rejection: Specimens other than serum.
Grossly hemolyzed, lipemic or icteric samples.
|
| Clinical Relevance | Anti-actin antibodies are found in 52-85% of patients with AIH or chronic active hepatitis and in 22% of patients with primary biliary cirrhosis . Anti-actin antibodies have been reported, usually in low titers, in 3-18% of sera from the general healthy population. |
| Antibodies |
- Anti-Smooth Muscle Antibodies (ASMA)
|
| Autoimmune Diseases |
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