| Test Number | 170 |
| Method | ELISA |
| Reference Range |
1 OR >1 Positive and <1 is Negative
|
| CPT Code | 83516 |
| Schedule Turnaround Time | Assay performed once per week. Report availability is within one week from the time of specimen receipt. |
| Specimen Requirements | Specimen need not be refrigerated or frozen. Collect 5-10 ml of blood in a red top or serum separator tube. If possible, separate serum from clot and place into orange tube provided with IMMCO collection kits. Do not puncture top of orange tube. If separation facilities are not available, the blood can be sent in the tube used for collection. |
| Sample Stability | Sample is stable at ambient temperature during shipment. If sample is stored prior to shipment, it is stable refrigerated (2-8˚C) up to five days and frozen (-20˚C or lower) up to one year. |
| Clinical Relevance | ASGPR is a liver specific membrane receptor playing a pivotal role in the endocytosis of glycoproteins from the blood. Anti-ASGPR are detected in 88% of patients with
McFarlane BM, McSorley CG, Vergani D, McFarlane IG, Williams R: Serum autoantibodies reacting with the hepatic
asialoglycoprotein receptor protein (hepatic lectin) in acute and chronic liver disorders. J Hepatol 1986 3, 196-205
Treichel U, Poralla T., Hess G, Manns M, Meyer zum Buschenfelde KH: Autoantibodies to human asialoglycoprotein
receptor in autoimmune-type chronic hepatitis. Hepatology 1990 11, 606-612
|
| Antibodies |
- Anti-Liver/Kidney/Microsomal 1 (LKM-1) Antibodies
- Anti-Mitochondrial Antibodies
- Anti-Mitochondrial M2 Antibodies
- Anti-Smooth Muscle Antibodies (ASMA)
|
| Autoimmune Diseases |
|